BDBM333993 (S)-1-(3-((8-(6-methoxy-5- methylpyridin-3-yl)-9-methyl- 9H-purin-6-yl)oxy)pyrrolidin-1- yl)propan-1-one::US9730940, Compound 2-94

SMILES CCC(=O)N1CCC(C1)Oc1ncnc2n(C)c(nc12)-c1cnc(OC)c(C)c1

InChI Key InChIKey=QSQWBLGJRMXEAK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333993   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM333993((S)-1-(3-((8-(6-methoxy-5- methylpyridin-3-yl)-9-m...)Copy SMILESCopy InChI

Affinity DataIC50: 2.10nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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