BDBM333994 (S)-1-(3-((8-(2-(tert- butyl)thiazol-5-yl)-9-ethyl-9H- purin-6-yl)oxy)pyrrolidin-1- yl)propan-1-one::US9730940, Compound 2-95

SMILES CCC(=O)N1CCC(C1)Oc1ncnc2n(CC)c(nc12)-c1cnc(s1)C(C)(C)C

InChI Key InChIKey=JTHONZVZMDZBJR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 333994   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM333994((S)-1-(3-((8-(2-(tert- butyl)thiazol-5-yl)-9-ethyl...)Copy SMILESCopy InChI

Affinity DataIC50: 2.20nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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