BDBM334021 9-ethyl-8-(2-methylpyrimidin-5- yl)-6-{[(3S)-1-((R or S)- spiro[2.4]hept-1- ylcarbonyl)pyrrolidin-3-yl]oxy}- 9H-purine::US9730940, Compound 2-122::US9730940, Compound 2-123

SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)C3CC33CCCC3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=ULHNTBRHYKHWQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334021   

LigandPNGBDBM334021(US9730940, Compound 2-123 | 9-ethyl-8-(2-methylpyr...)
Affinity DataIC50: 16nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
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LigandPNGBDBM334021(US9730940, Compound 2-123 | 9-ethyl-8-(2-methylpyr...)
Affinity DataIC50: 1nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent