BDBM334030 (1S,2S)- or (1R,2R)-{[(3S)-3- {[9-ethyl-8-(2-methylpyrimidin- 5-yl)-9H-purin-6- yl]oxy}pyrrolidin-1- yl]carbonyl}cyclopropyl) methanol::US9730940, Compound 2-130::US9730940, Compound 2-131

SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)C3CC3CO)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=TXMIMJSZJAANMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 334030   

LigandPNGBDBM334030(US9730940, Compound 2-131 | (1S,2S)- or (1R,2R)-{[...)
Affinity DataIC50: 1.40nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
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LigandPNGBDBM334030(US9730940, Compound 2-131 | (1S,2S)- or (1R,2R)-{[...)
Affinity DataIC50: 46nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent