BDBM334110 6-({(3S)-1-[(3,3- difluorocyclobutyl)carbonyl]pyr- rolidin-3-yl}oxy)-9-ethyl-8-(6- methoxypyridin-3-yl)-9H-purine::US9730940, Compound 3-51

SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)C3CC(F)(F)C3)ncnc12)-c1ccc(OC)nc1

InChI Key InChIKey=SJBVHXWMIHMJQF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334110   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM334110(6-({(3S)-1-[(3,3- difluorocyclobutyl)carbonyl]pyr-...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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