BDBM334126 (S)-(3-((9-ethyl-8-(1-ethyl-5- methyl-1H-pyrazol-4-yl)-9H- purin-6-yl)oxy)pyrrolidin-1- yl)(tetrahydro-2H-pyran-4- yl)methanone::US9730940, Compound 3-61

SMILES CCn1ncc(c1C)-c1nc2c(O[C@H]3CCN(C3)C(=O)C3CCOCC3)ncnc2n1CC

InChI Key InChIKey=SYWDSJRCKJADOW-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334126   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM334126((S)-(3-((9-ethyl-8-(1-ethyl-5- methyl-1H-pyrazol-4...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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