BDBM334127 US9730940, Compound 3-62::racemic-6-{[1- (cyclopropylcarbonyl)-4,4- dimethylpyrrolidin-3-yl]oxy}-9- ethyl-8-(2-methylpyrimidin-5- yl)-9H-purine

SMILES CCn1c(nc2c(O[C@@H]3CN(CC3(C)C)C(=O)C3CC3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=PMHPMPPFRACMCA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334127   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM334127(racemic-6-{[1- (cyclopropylcarbonyl)-4,4- dimethyl...)Copy SMILESCopy InChI

Affinity DataIC50: 2.30nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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