BDBM334158 6-{[(3S)-1-(azetidin-1- ylcarbonyl)pyrrolidin-3-yl]oxy}- 9-ethyl-8-(2-methylpyrimidin-5- yl)-9H-purine::US9730940, Compound 5-11

SMILES CCn1c(nc2c(O[C@H]3CCN(C3)C(=O)N3CCC3)ncnc12)-c1cnc(C)nc1

InChI Key InChIKey=SRJXXDDAMCNELH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 334158   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM334158(6-{[(3S)-1-(azetidin-1- ylcarbonyl)pyrrolidin-3-yl...)Copy SMILESCopy InChI

Affinity DataIC50: 1.30nMAssay Description:The PI3-Kinase biochemical assay was optimized using the HTRF kit provided by Upstate (Millipore). The assay kit contains six reagents: 1) 4× Reactio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2019
Entry Details
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