BDBM33420 pyrimidinol carboxylic acid, 12

SMILES COC(=O)c1nc(Cc2ccccc2)[nH]c(=O)c1O

InChI Key InChIKey=MGZAUOBOIKCIEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33420   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM33420(pyrimidinol carboxylic acid, 12)
Affinity DataIC50: 7.20E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2009
Entry Details Article
PubMed