BDBM335498 (1S,3R,4R,12aR)-3-fluoro-7-hydroxy-6,8-dioxo-N-(2,4,6-trifluorobenzyl)-1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1′,2′-d]pyrazine-9-carboxamide::US9732092, Compound 82

SMILES Oc1c2C(=O)N3[C@@H]4C[C@@H](C[C@H]4F)[C@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335498   

TargetSolute carrier family 22 member 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM335498((1S,3R,4R,12aR)-3-fluoro-7-hydroxy-6,8-dioxo-N-(2,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent