BDBM335510 (1R,3S,5R)-2-(2-(3-acetyl-6- (cyclopropylmethoxy)-1H- indol-1-yl)acetyl)-N-(3- chloro-2-fluorobenzyl)-2- azabicyclo[3.1.0]hexane-3- carboxamide::US10550140, Compound 3::US9732104, Compound 3

SMILES CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCC3CC3)ccc12

InChI Key InChIKey=QOQJNCWMUYWVGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335510   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335510((1R,3S,5R)-2-(2-(3-acetyl-6- (cyclopropylmethoxy)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335510((1R,3S,5R)-2-(2-(3-acetyl-6- (cyclopropylmethoxy)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent