BDBM335529 (3-acetyl-1-(2-((2S,4R)- 2-((R)-1-(3-chloro-2- fluorophenyl)ethyl- carbamoyl)-4- fluoropyrrolidin-1-yl)-2- oxoethyl)-1H-indol-6- yloxy)methylphosphonic acid::US10550140, Compound 19::US9732104, Compound 19

SMILES C[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1C(=O)Cn1cc(C(C)=O)c2ccc(OCP(O)(O)=O)cc12)c1cccc(Cl)c1F

InChI Key InChIKey=TVJQGMBOZSFLCO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335529   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335529(US9732104, Compound 19 | (3-acetyl-1-(2-((2S,4R)- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335529(US9732104, Compound 19 | (3-acetyl-1-(2-((2S,4R)- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent