BDBM335536 (3-acetyl-1-(2-((2S,4R)-4- fluoro-2-(3-phenoxy- phenylcarbamoyl)pyrrolidin- 1-yl)-2-oxoethyl)-1H-indol- 6-yloxy)methylphosphonic acid::US10550140, Compound 26::US9732104, Compound 26

SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Oc3ccccc3)c2)c2cc(OCP(O)(O)=O)ccc12

InChI Key InChIKey=AKMTXZMTLXRRGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335536   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335536(US9732104, Compound 26 | (3-acetyl-1-(2-((2S,4R)-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM335536(US9732104, Compound 26 | (3-acetyl-1-(2-((2S,4R)-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent