BDBM335605 (3R,4R)-4-amino-1-((4-((3-(5-isopropyl-1,3,4-thiadiazol-2-yl)phenyl)amino)pyrrolo[2,1-f][1,2,4]triazin-5-yl)methyl)piperidin-3-ol::US9737542, Example 48

SMILES CC(C)c1nnc(s1)-c1cccc(Nc2ncnn3ccc(CN4CC[C@H]([C@H](O)C4)N(Cc4ccccc4)C(=O)OC(C)(C)C)c23)c1

InChI Key InChIKey=VWGVVEZELZJKOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335605   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335605(US9737542, Example 48 | (3R,4R)-4-amino-1-((4-((3-...)
Affinity DataIC50: 55nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
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Date in BDB:
7/1/2019
Entry Details
US Patent