BDBM335717 5-(Ethyl(tetrahydro-2H-pyran-4- yl)amino)-N-((8-fluoro-1-methyl- 3-oxo-2,3-dihydroisoquinolin-4- yl)methyl)-4-methyl-4'- (morpholinomethyl)-[1,1'- biphenyl]-3-carboxamide::US9738630, Example 12

SMILES CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c3cccc(F)c3c(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=AELNQLUHQWVZNC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335717   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM335717(US9738630, Example 12 | 5-(Ethyl(tetrahydro-2H-pyr...)
Affinity DataEC50: <5.00E+3nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of hitone methyl transferases can be readily tested by assays known to those sk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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