BDBM335732 US9738640, Example 5

SMILES Fc1cc(ccc1Cl)C(=O)Nc1ccc2n(ccc2n1)C(=O)c1ccc(Cl)c(F)c1

InChI Key InChIKey=UQMSRHQRAORWGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335732   

TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

US Patent
LigandPNGBDBM335732(US9738640, Example 5)
Affinity DataIC50: 1.00E+4nMAssay Description:Recombinant human MAO-A enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7316). The assay was carried out i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
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TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

US Patent
LigandPNGBDBM335732(US9738640, Example 5)
Affinity DataIC50: 27.5nMAssay Description:Recombinant human MAO-B enzyme, expressed in baculovirus-infected insect cells, was purchased from Sigma-Aldrich (M7441). The assay was performed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
Go to US Patent