BDBM336307 4-(1-(2-chloro-6- cyclypropoxybenzoyl)-1H- indazol-3-yl)benzoic acid::US9745265, 1H

SMILES OC(=O)c1ccc(cc1)-c1nn(C(=O)c2c(Cl)cccc2OC2CC2)c2ccccc12

InChI Key InChIKey=QHDQWVCHGBISAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 336307   

TargetNuclear receptor ROR-gamma(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336307(4-(1-(2-chloro-6- cyclypropoxybenzoyl)-1H- indazol...)
Affinity DataIC50: 39nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent