BDBM336754 2-({(3R,6R)-1-[(2- ethoxyphenyl) carbonyl]-6- methylpiperidin- 3-yl}oxy)-4- methoxypyridine::US9745284, 14

SMILES CCOc1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)Oc1cc(OC)ccn1

InChI Key InChIKey=XATLKABOKHROMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336754   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336754(2-({(3R,6R)-1-[(2- ethoxyphenyl) carbonyl]-6- meth...)
Affinity DataIC50: 34.8nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336754(2-({(3R,6R)-1-[(2- ethoxyphenyl) carbonyl]-6- meth...)
Affinity DataIC50: 1.98E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent