BDBM336787 1-(4-methoxy-2- {[(3R,6R)-6- methyl-1-{[2-(2H- 1,2,3-triazol-2- yl)phenyl]carbonyl} piperidin-3- yl]oxy}pyridin- 3-yl)ethanone::US9745284, 51

SMILES COc1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1C(C)=O

InChI Key InChIKey=DGAOPKUYPKCBLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 336787   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336787(1-(4-methoxy-2- {[(3R,6R)-6- methyl-1-{[2-(2H- 1,2...)
Affinity DataIC50: 12.3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM336787(1-(4-methoxy-2- {[(3R,6R)-6- methyl-1-{[2-(2H- 1,2...)
Affinity DataIC50: 976nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent