BDBM337265 2-[2-(3,5-dimethoxyphenyl)ethyl]-6-[4-(4-ethylpiperazin-1-yl)phenyl]-5H-pyrrolo[2,3-b]pyrazine::US9745311, Example 2

SMILES CCN1CCN(CC1)c1ccc(cc1)-c1cc2nc(CCc3cc(OC)cc(OC)c3)cnc2[nH]1

InChI Key InChIKey=DUFSIPGGMRUUNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 337265   

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM337265(US9745311, Example 2 | 2-[2-(3,5-dimethoxyphenyl)e...)
Affinity DataIC50: 100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM337265(US9745311, Example 2 | 2-[2-(3,5-dimethoxyphenyl)e...)
Affinity DataIC50: 100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM337265(US9745311, Example 2 | 2-[2-(3,5-dimethoxyphenyl)e...)
Affinity DataIC50: 100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent