BDBM337274 2-[2-(3,5-dimethoxyphenyl)ethyl]-6-(2-methylphenyl)-5H-pyrrolo[2,3-b]pyrazine::US9745311, Example 9

SMILES COc1cc(CCc2cnc3[nH]c(cc3n2)-c2ccccc2C)cc(OC)c1

InChI Key InChIKey=GQMBGTUPSOKVFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 337274   

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM337274(US9745311, Example 9 | 2-[2-(3,5-dimethoxyphenyl)e...)
Affinity DataIC50: 100nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM337274(US9745311, Example 9 | 2-[2-(3,5-dimethoxyphenyl)e...)
Affinity DataIC50: 300nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM337274(US9745311, Example 9 | 2-[2-(3,5-dimethoxyphenyl)e...)
Affinity DataIC50: 1.60E+3nMAssay Description:The inhibitor potency of compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to detect product fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent