BDBM337377 4,6-Dimethyl-5-[2-methyl-4-(1,2,3,4-tetrahydro-1,6-naphthyridin-5-yloxy)phenyl]pyridazin-3(2H)-one (15)::US9745317, 15

SMILES Cc1cc(Oc2nccc3N(Cc4ccccc4)CCCc23)ccc1-c1c(C)nn(C2CCCCO2)c(=O)c1C

InChI Key InChIKey=PDPFKKDCWPHXIB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337377   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM337377(US9745317, 15 | 4,6-Dimethyl-5-[2-methyl-4-(1,2,3,...)
Affinity DataKi:  18.1nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent