BDBM339881 US9757383, Example 4::trans-4-[{3-[5-({[(2R)-2-hydroxy-2-(8-hydroxy-2-ox-1,2-dihydroquinolin-5-yl)ethyl]amino}methyl)-1H-indol-1-yl]propyl}(methyl)amino]cyclohexyl hydroxy(di-2-thienyl)acetate

SMILES CN(CCCn1ccc2cc(CNC[C@H](O)c3ccc(O)c4NCC=Cc34)ccc12)[C@H]1CC[C@@H](CC1)OC(=O)C(O)(c1cccs1)c1cccs1

InChI Key InChIKey=HIUWSDVYOJMZKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 339881   

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM339881(US9757383, Example 4 | trans-4-[{3-[5-({[(2R)-2-hy...)
Affinity DataIC50: 220nMAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM339881(US9757383, Example 4 | trans-4-[{3-[5-({[(2R)-2-hy...)
Affinity DataIC50: 0.600nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent