BDBM339970 (R)-tert-butyl (1-((6-chloro-5-cyanopyrazin-2-yl)amino)-3-methoxypropan-2-yl)carbamate::US9775839, 1.1

SMILES COC[C@@H](CNc1cnc(C#N)c(Cl)n1)NC(=O)OC(C)(C)C

InChI Key InChIKey=WPQPXRZNTONAIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339970   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM339970((R)-tert-butyl (1-((6-chloro-5-cyanopyrazin-2-yl)a...)
Affinity DataIC50: 528nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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