BDBM340005 (S)-5-((2-Aminopropyl)amino)-3-(phenylethynyl)pyrazine-2-carboxamide::US9775839, 11.1

SMILES C[C@H](N)CNc1cnc(C(N)=O)c(n1)C#Cc1ccccc1

InChI Key InChIKey=IZSNMMBEZFRIBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340005   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340005((S)-5-((2-Aminopropyl)amino)-3-(phenylethynyl)pyra...)
Affinity DataIC50: 992nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
Go to US Patent