BDBM340007 (2-(6-(((3S,4S)-4-amino-1,1-dioxidotetrahydro-2H-thiopyran-3-yl)amino)-3-carbamoylpyrazin-2-yl)-1H-indol-3-yl)dimethylsulfonium::US9775839, 12.2

SMILES C[S+](C)c1c([nH]c2ccccc12)-c1nc(N[C@@H]2CS(=O)(=O)CC[C@@H]2N)cnc1C(N)=O

InChI Key InChIKey=RCCFSRGKPGDJHP-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340007   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM340007((2-(6-(((3S,4S)-4-amino-1,1-dioxidotetrahydro-2H-t...)
Affinity DataIC50: 2.47E+3nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2019
Entry Details
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