BDBM340218 (2S,3S,4S)-1-(2-(3- acetyl-6-hydroxy-1H- indol-1-yl)acetyl)-N-(3- chloro-2-fluorobenzyl)- 3- (cyclopropylmethoxy)- 4-fluoropyrrolidine-2- carboxamide::US9758537, Compound 21

SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)[C@@H](OCC3CC3)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc12

InChI Key InChIKey=JMDWISIGBCRDQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340218   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340218(US9758537, Compound 21 | (2S,3S,4S)-1-(2-(3- acety...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent