BDBM340249 (2S,4R)-N-(3-chloro-2- fluorobenzyl)-4-fluoro- 1-(2-(3-iodo-1H- pyrazolo[3,4-c]pyridin- 1-yl)acetyl)pyrrolidine- 2-carboxamide::US9758537, Compound 52

SMILES F[C@@H]1C[C@H](N(C1)C(=O)Cn1nc(I)c2ccncc12)C(=O)NCc1cccc(Cl)c1F

InChI Key InChIKey=IZUAUFBPNCXYPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340249   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340249(US9758537, Compound 52 | (2S,4R)-N-(3-chloro-2- fl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent