BDBM340297 1-(2-((1R,3S,5R)-3-(3- chloro-2- fluorobenzylcarbamoyl)- 2-azabicyclo[3.1.0]hexan- 2-yl)-2-oxoethyl)-1H- thieno[3,2-c]pyrazole-3- carboxamide::US9758537, Compound 107

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccsc12

InChI Key InChIKey=UVEQCISZYZETQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340297   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340297(US9758537, Compound 107 | 1-(2-((1R,3S,5R)-3-(3- c...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent