BDBM340313 (2S,4R)-1-(2-(3- carbamoyl-1H- pyrazolo[3,4-c]pyridin- 1-yl)acetyl)-4- fluoropyrrolidine-2- carboxamide, N-(3- chloro-2- fluorophenylmethyl-d2)::US9758537, Compound 128

SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12

InChI Key InChIKey=OJYIIQKMGVNXSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 340313   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM340313(US9758537, Compound 128 | (2S,4R)-1-(2-(3- carbamo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent