BDBM340526 US9763922, Example 57

SMILES CN\C=C(/C(=N)C(F)(F)F)c1ccc(NC(=N)C2=C(CCN(C2)C(C)=O)NC2CCOC2)cn1

InChI Key InChIKey=RIHTXJCMDDEMDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340526   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM340526(US9763922, Example 57)
Affinity DataIC50: 10nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandPNGBDBM340526(US9763922, Example 57)
Affinity DataIC50: 2.49E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent