BDBM340750 US9763922, Example 276

SMILES CC(CO)n1nc(Nc2ccc(cc2)-c2cn(C)nc2C(F)(F)F)c2CN(CCc12)C(C)=O

InChI Key InChIKey=FYWUBFLMPOMTSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 340750   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandPNGBDBM340750(US9763922, Example 276)
Affinity DataIC50: 15nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Genentech

US Patent
LigandPNGBDBM340750(US9763922, Example 276)
Affinity DataIC50: 1.68E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2019
Entry Details
US Patent