BDBM3409 2-Butanol deriv. 17::N-tert-butyl-2-{4-[1-(tert-butylcarbamoyl)naphthalen-2-yl]-3-hydroxybutyl}naphthalene-1-carboxamide

SMILES CC(C)(C)NC(=O)c1c(CCC(O)Cc2ccc3ccccc3c2C(=O)NC(C)(C)C)ccc2ccccc12

InChI Key InChIKey=LHQZYXZCDMXJLV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3409   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals

LigandPNGBDBM3409(N-tert-butyl-2-{4-[1-(tert-butylcarbamoyl)naphthal...)
Affinity DataKi:  1.40E+3nM ΔG°:  -8.30kcal/molepH: 5.6 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2005
Entry Details Article
PubMed