BDBM341234 (S)-2,4-diamino-6-((1-(5-(3-morpholinopropyl)-4-oxo-3-phenyl-3,4-dihydroquinazoline-2-yl)ethyl)amino)pyrimidine-5-carbonitrile::US9765060, Compound 61

SMILES C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(CCCN3CCOCC3)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=OFGZBSYIKRDFFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 341234   

LigandPNGBDBM341234(US9765060, Compound 61 | (S)-2,4-diamino-6-((1-(5-...)
Affinity DataIC50: 0.600nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
US Patent