BDBM342166 (R)-1-benzyl-N-(9-methyl-6-oxo-6,7,8,9-tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazin-2-yl)-1H-pyrazole-4-carboxamide::US9771366, Compound 15

SMILES C[C@@H]1CNC(=O)c2cc3cc(NC(=O)c4cnn(Cc5ccccc5)c4)ccc3n12

InChI Key InChIKey=DWRUMXZDNGCUDK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 342166   

TargetRibosomal protein S6 kinase alpha-3(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM342166(US9771366, Compound 15 | (R)-1-benzyl-N-(9-methyl-...)
Affinity DataIC50: 6nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-6(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM342166(US9771366, Compound 15 | (R)-1-benzyl-N-(9-methyl-...)
Affinity DataIC50: 8nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM342166(US9771366, Compound 15 | (R)-1-benzyl-N-(9-methyl-...)
Affinity DataIC50: 23.6nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-2(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM342166(US9771366, Compound 15 | (R)-1-benzyl-N-(9-methyl-...)
Affinity DataIC50: 9.40E+4nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent