BDBM342169 6-(4-fluorophenyl)-4-[4-[4-methyl-5-[3- (trifluoromethoxy)phenyl]-1H-imidazol- 2-yl]-1-piperidyl]-7H-pyrrolo[2,3- d]pyrimidine::US9771369, Compound P-3011

SMILES Cc1nc([nH]c1-c1cccc(OC(F)(F)F)c1)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(F)cc1

InChI Key InChIKey=MIMAOXCZKVQPAQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342169   

LigandPNGBDBM342169(US9771369, Compound P-3011 | 6-(4-fluorophenyl)-4-...)
Affinity DataKi:  500nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM342169(US9771369, Compound P-3011 | 6-(4-fluorophenyl)-4-...)
Affinity DataKi:  5.50E+3nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent