BDBM342191 6-(4-fluorophenyl)-4-[4-[5-(4-methoxy- 3-methyl-phenyl)-4-methyl-1H- imidazol-2-yl]-1-piperidyl]-7H- pyrrolo[2,3-d]pyrimidine::US9771369, Compound P-3029

SMILES COc1ccc(cc1C)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(F)cc1

InChI Key InChIKey=AKRNEGNJJXZGNK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342191   

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM342191(US9771369, Compound P-3029 | 6-(4-fluorophenyl)-4-...)
Affinity DataKi:  500nMAssay Description:Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent

LigandPNGBDBM342191(US9771369, Compound P-3029 | 6-(4-fluorophenyl)-4-...)
Affinity DataKi:  500nMAssay Description:The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
US Patent