BDBM342685 5-[4-(Tetrahydro-furan-3-carbonyl)-piperazin-1-ylmethyl]-thiophene-2-carboxylic acid 2-trifluoromethoxy-benzylamide::US9776991, Example 55

SMILES FC(F)(F)Oc1ccccc1CNC(=O)c1ccc(CN2CCN(CC2)C(=O)C2CCOC2)s1

InChI Key InChIKey=YIWNMCURDFAVLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 342685   

TargetBifunctional epoxide hydrolase 2(Human)
Sanofi

US Patent
LigandPNGBDBM342685(5-[4-(Tetrahydro-furan-3-carbonyl)-piperazin-1-ylm...)
Affinity DataIC50: 1.05nMAssay Description:Compounds were tested in a biochemical screening assay using recombinant sEH purified from Sf9 insect cells and an artificial substrate, (3-phenyl-ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent