BDBM343171 (P)-1-(2-fluoro-5-methoxy-3''-(trifluoromethyl)-4-biphenylyl)-N-3-isoxazolyl-2-methyl-3-oxo-2,3-dihydro-6-isoquinolinesulfonamide::US9776995, Example 551::US9776995, Example 552

SMILES COc1cc(c(F)cc1-c1n(C)c(=O)cc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=RIYGGBOYMISEBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343171   

LigandPNGBDBM343171((P)-1-(2-fluoro-5-methoxy-3''-(trifluoromethyl)-4-...)
Affinity DataIC50: 28nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent

LigandPNGBDBM343171((P)-1-(2-fluoro-5-methoxy-3''-(trifluoromethyl)-4-...)
Affinity DataIC50: 1.25E+3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details
US Patent