BDBM343736 US9777008, Compound 30

SMILES COc1cc2CCN(CC(O)COc3cccc(CNC4CCCC4)c3)Cc2cc1OC

InChI Key InChIKey=DWUWWPGCKJJQRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343736   

LigandPNGBDBM343736(US9777008, Compound 30)
Affinity DataIC50: 4.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent

LigandPNGBDBM343736(US9777008, Compound 30)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human full length FLAG-tagged PRMT5/human His6-tagged MEP50 expressed in baculovirus-infected Sf9 cells assessed as reduction in tritiu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed