BDBM344204 (2R)-2-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl]carbamoyl}-4-oxo-6,7-dihydrofuro[3,2-c]pyridin-5(4H)-yl]propyl acetate::US9777020, Example 98

SMILES CCOc1nc(ccc1NC(=O)c1coc2CCN([C@H](C)COC(C)=O)C(=O)c12)N1CCN(CC1)C(C)=O

InChI Key InChIKey=XEDUTMAWRFIXCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344204   

TargetHigh affinity nerve growth factor receptor(Human)
Abbvie

US Patent
LigandPNGBDBM344204((2R)-2-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2019
Entry Details
US Patent