BDBM344301 (1S,3R*)-1-(3-Fluoro-2- methyl-phenyl)-3-(5- fluoropyridin-3-yl)-N- hydroxycyclopentanecarboxamide::US9783488, Example 10

SMILES Cc1c(F)cccc1[C@@]1(CC[C@H](C1)c1cncc(F)c1)C(=O)NO

InChI Key InChIKey=HZPQUCRMKHUJSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344301   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM344301((1S,3R*)-1-(3-Fluoro-2- methyl-phenyl)-3-(5- fluor...)
Affinity DataIC50: 140nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
Go to US Patent