BDBM344358 (1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3-(1-methyl-1H-pyrazol-5- yl)cyclopentanecarboxamide::US9783488, Example 50

SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](C1)c1ccnn1C)C(=O)NO

InChI Key InChIKey=RERSZXIBQVTMBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344358   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM344358((1S,3S*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- 3...)
Affinity DataIC50: 250nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
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