BDBM344359 (1S,3R*)-3-(1-(2-(diethylamino)ethyl)-1H-pyrazol-4-yl)-1-(3-fluoro-2-methylphenyl)-N-hydroxycyclopentanecarboxamide::US9783488, Example 51

SMILES CCN(CC)CCn1cc(cn1)[C@@H]1CC[C@@](C1)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=LHOKZZCIENTAEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344359   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM344359((1S,3R*)-3-(1-(2-(diethylamino)ethyl)-1H-pyrazol-4...)
Affinity DataIC50: 82nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
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