BDBM344399 (E)-N1-(4-chloro-3-(trifluoromethyl)phenyl)-N4-(3-fluoro-4-(6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)quinoline-4-yloxy)benzaldehyde)semicarbazone::US9783499, Example 51

SMILES COc1cc2c(Oc3ccc(\C=N\N(C(N)=O)c4ccc(Cl)c(c4)C(F)(F)F)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=YHUHLXIQIRDFMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344399   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344399((E)-N1-(4-chloro-3-(trifluoromethyl)phenyl)-N4-(3-...)
Affinity DataIC50: 690nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent