BDBM344402 (E)-N1-phenyl-N4-(3-fluoro-4-(6-methoxy-7-(3-(morpholin-4-yl)prop oxy)quinoline-4-yloxy)benzaldehyde)semicarbazone::US9783499, Example 55

SMILES COc1cc2c(Oc3ccc(\C=N\N(C(N)=O)c4ccccc4)cc3F)ccnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=DFPGPTPQJNNWCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344402   

TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

US Patent
LigandPNGBDBM344402((E)-N1-phenyl-N4-(3-fluoro-4-(6-methoxy-7-(3-(morp...)
Affinity DataIC50: 500nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent