BDBM344725 1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 27

SMILES Cc1noc(C)c1CN1CCN(C1=O)c1cccc2n(ncc12)-c1ccccc1F

InChI Key InChIKey=LYJWKXNBBNLHJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 344725   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344725(1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-3-[1-(2-f...)
Affinity DataIC50: 546nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent

LigandPNGBDBM344725(1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-3-[1-(2-f...)
Affinity DataIC50: 1.04E+3nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent