BDBM344797 1-[1-(2-fluorophenyl)-1H-::1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(8aS)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-2-oxoethyl}imidazolidin-2-one::US9783527, Example 99

SMILES Fc1ccccc1-n1ncc2c(cccc12)N1CCN(CC(=O)N2CCN3CCC[C@H]3C2)C1=O

InChI Key InChIKey=HMJOKXLVCLCOMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344797   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344797(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(8aS)...)
Affinity DataIC50: 482nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent