BDBM344937 1-[(2,5-dimethyl-1,3-::1-[(2,5-dimethyl-1,3-thiazol-4-yl)methyl]-3-[1-(2-fluorophenyl)-1H-indazol-4-yl]imidazolidin-2-one::US9783527, Example 239

SMILES Cc1nc(CN2CCN(C2=O)c2cccc3n(ncc23)-c2ccccc2F)c(C)s1

InChI Key InChIKey=CCUNWSGHKGTIDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344937   

TargetSodium channel protein type 9 subunit alpha(Human)
Abbvie

US Patent
LigandPNGBDBM344937(1-[(2,5-dimethyl-1,3-thiazol-4-yl)methyl]-3-[1-(2-...)
Affinity DataIC50: 352nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details
US Patent