BDBM345229 (1S,3S*)-3-(7-Fluoro-1- methyl-1H-indazol-6-yl)-1- (3-fluoro-2-methylphenyl)- N- hydroxycyclopentanecarboxamide::US9783488, Example 82

SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](C1)c1ccc2cnn(C)c2c1F)C(=O)NO

InChI Key InChIKey=CFMBAUBXRNMZPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345229   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM345229((1S,3S*)-3-(7-Fluoro-1- methyl-1H-indazol-6-yl)-1-...)
Affinity DataIC50: 110nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
Go to US Patent